Status of immunity cellular link in diabetic foot syndrome

  • O. Y. Khomko Bukovinian State Medical University
  • R. I. Sydorchuk Bukovinian State Medical University
  • P. M. Volyanyuk Bukovinian State Medical University
  • O. A. Karliychuk Bukovinian State Medical University
  • B. V. Petryuk Bukovinian State Medical University
  • I. I. Bilyk Bukovinian State Medical University
  • R. P. Knut Bukovinian State Medical University
Keywords: diabetic foot syndrome, pathogenesis, cell link of immunity systemic, immune disorders

Abstract

Changes in the cell link of the immune system in patients with diabetic foot syndrome are considered. In patients the trend is observed of 28.7% increase in the absolute quantity of total pool of T–lymphocytes, but 16.50% reduction of their relative quantity. This formed the first (in 62.5% of patients) and second (37.5%) grade of immune disorders in systemic immunity cellular link were revaled. A possible reason for these changes is that the pathogens of purulent–necrotic processes of soft tissues are conventionally pathogenic microorganisms localized in the extracellular space, against which mainly humoral immune response is formed; in contrast to the immune response in relation to intracellular pathogens that is provided by cellular link immunity.

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Published
2017-09-07
How to Cite
Khomko, O. Y., Sydorchuk, R. I., Volyanyuk, P. M., Karliychuk, O. A., Petryuk, B. V., Bilyk, I. I., & Knut, R. P. (2017). Status of immunity cellular link in diabetic foot syndrome. Klinicheskaia Khirurgiia, (8), 48-49. https://doi.org/10.26779/2522-1396.2017.08.48
Section
General Problems of Surgery