Clinic-morphological diagnosis of Barrett’s esophagus

Keywords: Barrett’s esophagus; metaplasia; dysplasia; аdenocarcinoma; morphological verification

Abstract

Objective. Determination of efficacy of morphological diagnosis of the Barrett’s esophagus (BE).

Маterials and methods. Diagnosis of BE in accordance to data obtained during screening endoscopic investigation with biopsy and morphological verification in 2014 - 2016 yrs, basing on Medical Centre «University Clinic «Оberig», Kyiv, was analyzed.

Results. BE was diagnosed in 841 (36.8%) patients (95% of confidence interval (CІ) 36.02 – 39.76) among 2405 patients, in whom esophagogastroscopy was conducted. Histologically cardiac metaplasia was revealed in 48 (5.71%) patients, fundic - in 136 (16.19%), intestinal specialized - in 625 (72.28%), and the mixed - in 32 (3.81%) patients. Dysplasia of high and low grades was diagnosed in 32 (3.81%) (95% CІ 2.04 – 4.62), including: in 24 (75.0%) - low, and in 8 (25.0%) – high. Аdenocarcinoma was revealed in 4 (0.47%) patients (95% CІ 0.20 – 1.36).

Conclusion. Мorphological verdict constitutes the main and objective criterion for the BE verification, what is important for selection of the treatment tactics and certainly help to determine the disease prognosis.

Author Biographies

O. G. Кuryk, Scientific-Practical Centre of Prophylactic and Clinical Medicine, Kyiv, Bogomolets National Medical University, Kyiv

Olena Georhiivna Kuryk - doctor of medical sciences, the main scientific collaborator of the scientific miniinvasive surgery department of the State scientific institution “Scientific-practical centre of preventive and clinical medicine” State Administration of Affairs; Kyiv,
Verhnia street 5. Phone: 044 284 6272 ;
Mobile: 067-647-17-35.
Phone: 044 234 4062
e-mail: O_Kurik@ukr.net
ORCID ID: https://orcid.org/0000-0003-3093-4325

М. Yu. Коlomoiets, Scientific-Practical Centre of Prophylactic and Clinical Medicine, Kyiv

Mykhailo Yuriyovich Kolomoiets - doctor of medical sciences, professor, , laureate of the State prize of Ukraine in the branch of science and technics, Deputy Director for Scientific work of the State scientific institution “Scientific-practical centre of preventive and clinical medicine” State Administration of Affairs;
Kyiv, Verhnia street 5.
Phone: 044 284 9931; Mobile: 050-918-40-05.
e-mail: Mkolomoiets@gmail.com
ORCID ID: orcid.org/0000-0003-4860-624X

V. О. Yakovenko, Scientific-Practical Centre of Prophylactic and Clinical Medicine, Kyiv, Bogomolets National Medical University, Kyiv, Medical Centre «University Clinic «Оberig», Kyiv

Vladislav Aleksandrovich Yakovenko - candidate of medical sciences,chief of endoscopy and miniinvasive surgery department of Medical centre “Oberig clinic”,
03057, Kyiv, Zoologichna street, 3B.
Phone: 044 251 0303; Mobile: 050-381-81-30.
Scientific collaborator of the scientific miniinvasive surgery department of the State scientific institution “Scientific-practical centre of preventive and clinical medicine” State Administration of Affairs;
Kyiv, Verhnia street 5.
e-mail: yvladislav@ukr.net
ORCID ID: orcid.org/0000-0002-2419-6971

Т. V. Теreshchenko Т. V. Теreshchenko, Bogomolets National Medical University, Kyiv

Tatyana Viloriyivna Tereshchenko – assistant of chair of Pathological Anatomy
Bogomolets National Medical University;
Kyiv, Shevchenko boulevard 17.
Phone: 044 234 4062; Mobile: 096-833-32-04.
e-mail: tereshchenkotanya3@gmail.com
ORCID ID: https://orcid.org/0000-0002-9031-7647

R. P. Тkachenko, Scientific-Practical Centre of Prophylactic and Clinical Medicine, Kyiv

Tkachenko Rimma Petrivna - candidate of medical sciences, scientific collaborator of the scientific miniinvasive surgery department
State scientific institution “Scientific-practical centre of preventive and clinical medicine” State Administration of Affairs;
Kyiv, Verhnia street 5.
Phone: 044 284 6272, Mobile: 067-700-68-27.
e-mail: rimmatkachenko@i.ua
ORCID ID: https://orcid.org/0000-0003-3775-8002

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Published
2018-07-26
How to Cite
КurykO. G., КоlomoietsМ. Y., YakovenkoV. О., Т. V. ТеreshchenkoТ. V. Т., & ТkachenkoR. P. (2018). Clinic-morphological diagnosis of Barrett’s esophagus. Klinicheskaia Khirurgiia, 85(7), 9-12. https://doi.org/10.26779/2522-1396.2018.07.09
Section
General Problems of Surgery