Clinico-morphological peculiarities of the toothed colorectal neoplastic tumors

Keywords: large bowel; toothed, papillary-tubular neoplastic tumors; іndex of detection

Abstract

Objective. To analyze the observations of the toothed neoplastic tumors (TNT), using determination of their occurrence rate and peculiarities of morphological structure.

Маterials and methods. Results of morphological investigation were analyzed, concerning material, obtained during diagnostic colonoscopy (DCS) with biopsy, conducted in 376 patients.

Results. In 289 (77.0%) patients of 376 there were revealed 1058 colorectal superficial neoplastic tumors (CSNT). Іndex of detection of CSNT (quantity of diagnosed CSNT in relation to general quantity of the patients examined) have constituted 2.81. Of 376 patients TNT was diagnosed in 157 (42%) (95% confidence interval (CІ) 32.6-53.5), papillary-tubular neoplastic tumors (PTNT) - in 248 (66%) (95% CІ 58.2-70.8), while in 116 (31%) patients were observed simultaneously PTNT and TNT (95% CІ 28.6-42.7). Among 1058 CSNT were diagnosed 672 (63.5%) PTNT and 386 (36.5%) TNT, thus TNT was revealed trustworthily less frequently, than PTNT (р < 0.01; the odds ratio 2.69). Among 386 TNT were diagnosed 95 (24.6%) hyperplastic polyps, 144 (37.2%) TNT on a wide base, 74 (19.4%) conventional and 73 (18.8%) nonclassified.

Conclusion. TNT constitutes a prevalent colorectal pathology. DCS with excision of TNT is еffective method of prophylaxis of colorectal cancer.

Author Biographies

O. G. Kuryk, Scientific-Practical Centre of Prophylactic and Clinical Medicine of the State Affairs Management, Kyiv, Bogomolets National Medical University, Kyi

Olena Georhiivna Kuryk, - doctor of medical sciences,

main scientific collaborator

scientific miniinvasive surgery department  

Scientific-practical centre of preventive and clinical medicine

Kyiv, Verhnia street 5.

Phone: 044 284 6272 ;  

Professor of chair of Pathological Anatomy

Bogomolets National Medical University;

Kyiv, Shevchenko boulevard 17.

Phone: 044 234 4062

e-mail: O_Kurik@ukr.net          

ORCID ID: orcid.org /0000-0003-3093-4325

M. Yu. Kolomoiets, Scientific-Practical Centre of Prophylactic and Clinical Medicine of the State Affairs Management, Kyiv

Mykhailo Yuriyovich Kolomoiets - doctor of medical sciences, professor,

laureate of the State prize of Ukraine in the branch of science and technics,

Deputy Director

Scientific-practical centre of preventive and clinical medicine

Kyiv, Verhnia street 5.

Phone: 044 284 9931

e-mail: Mkolomoiets@gmail.com     

ORCID ID:  orcid.org/0000-0003-4860-624X

V. O. Yakovenko, Scientific-Practical Centre of Prophylactic and Clinical Medicine of the State Affairs Management, Kyiv, Bogomolets National Medical University, Kyiv, Medical Centre “Universal Clinic “Oberig”, Kyiv

Vladislav Aleksandrovich Yakovenko - candidate PhD

chief of endoscopy and miniinvasive surgery department

Medical centre “Oberig clinic”,

03057, Kyiv, Zoologichna street, 3B.

 Phone: 044 251 0303;  

e-mail: yvladislav@ukr.net          

ORCID ID: orcid.org/0000-0002-2419-6971

O. S. Gubar, Scientific-Practical Centre of Prophylactic and Clinical Medicine of the State Affairs Management, Kyiv

Olexandr Sergeyevich Gubar - PhD,

scientific collaborator of the scientific miniinvasive surgery department

Scientific-practical centre of preventive and clinical medicine

Phone: 044 284 6272

alex_gubar@ukr.net          

 orcid.org/0000-0003-4486-2377

R. P. Tkachenko, Scientific-Practical Centre of Prophylactic and Clinical Medicine of the State Affairs Management, Kyiv

Rimma Petrivna Tkachenko - PhD,

scientific collaborator of the scientific miniinvasive surgery department

Scientific-practical centre of preventive and clinical medicine

Kyiv, Verhnia street 5.

Phone: 044 284 6272,

 e-mail: rimmatkachenko@i.ua   

ORCID ID:  orcid.org/0000-0003-3775-8002

V. V. Bazdyrev, Medical Clinic “Innovation”, Kyiv

Vadim Vladimirovich Bazdyrev– PhD,

chief of pathomorphology laboratory

 medical clinic “Innovacia”.

Kyiv region, s. Lutizh , Vitryanogo str., 69a.

 Phone: 044 331 21 00      

vadim.bazdyrev@innovacia.com.ua

ORCID ID:  orcid.org/0000-0002-6092-418X

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Published
2018-08-30
How to Cite
Kuryk, O. G., Kolomoiets, M. Y., Yakovenko, V. O., Gubar, O. S., Tkachenko, R. P., & Bazdyrev, V. V. (2018). Clinico-morphological peculiarities of the toothed colorectal neoplastic tumors. Klinicheskaia Khirurgiia, 85(8), 62-64. https://doi.org/10.26779/2522-1396.2018.08.62
Section
General Problems of Surgery