Multidisciplinary approach in surgical treatment of the suprarenal gland pheochromocytoma

Keywords: pheochromocytoma; laparoscopy; multidisciplinary approach; аdrenalectomy; hemodynamical instability

Abstract

Objective. To estimate the results of the multidisciplinary approach application in treatment of the suprarenal gland pheochromocytoma.

Маterials and methods. Results of laparoscopic adrenalectomy (LА), performed for pheochromocytoma in 31 patients in 2015 - 2017 yrs, were investigated prospectively and retrospectively for analysis of efficacy of the perioperative treatment scheme. The patients were divided into two Groups: Group I - 15 patients, in whom perioperative treatment was conducted, using multidisciplinary approach, and Group II - 16 patients, in whom LA was conducted only. Median time of the operative intervention conduction, average volume of intraoperative blood loss, hemodynamical indices and complications are analyzed.

Results. Average volume of intraoperative blood loss in the Group I have constituted (48.7 ± 9.1) ml, in the Group II - (231.3 ± 113.8) ml (р < 0.05), median level of metanephrine in urine before adrenalectomy - accordingly, - (290.9 ± 71.8) and (991.2 ± 703.0) mcg/day (р < 0.05). Median duration of operative treatment  in the group I patients have constituted (117.7 ± 52.1) min and was nonessentially lesser, comparing with the Group II patients - (164.7 ± 57.5) min (р = 0.133). Hemodynamical instability was observed in 5 patients of Group II only. Median terms of postoperative treatment in the Group I patients have constituted (5.9 ± 2,2) days, and in Group II - (11.3 ± 5.4) days (p < 0.05). Complications have occurred in 2 (12.5%) patients of Group II. All the patients of Groups I-II have survived the treatment.

Conclusion. In patients with suprarenal gland pheochromocytoma a perioperative treatment, using multidisciplinary approach, is safe, effective and less durable, comparing with the LA conduction only.

Author Biographies

A. V. Skums, Shalimov National Institute of Surgery and Transplantology, Kyiv

Anatolii Skums, PhD

Chief of Department 

Surgeon oncologist, Department of combined pathology and retroperitoneal surgery,

Shalimov National Institute of Surgery and Transplantology,

Address: 30 HeroivSevastopolya Str., 03680, Kyiv, Ukraine, tel.: +38 (044)4542079

email: skums.av@gmail.com

https://orcid.org/0000-0002-2350-6245

O. M. Gulko, Shalimov National Institute of Surgery and Transplantology, Kyiv

Oleh Gulko, PhD

Surgeon oncologist, Department of combined pathology and retroperitoneal surgery,

Shalimov National Institute of Surgery and Transplantology,

Adress: 30 HeroivSevastopolya Str., 03680, Kyiv, Ukraine, tel.: +38 (044)4542079

email: gulkoleg@gmail.com

https://orcid.org/0000-0001-8191-7141

B. A. Kondratiuk, Shalimov National Institute of Surgery and Transplantology, Kyiv

Vadym Kondratiuk, PhD

senior researcher Department of Endovascular Surgery

Shalimov National Institute of Surgery and Transplantology,

Address: 30 HeroivSevastopolya Str., 03680, Kyiv, Ukraine, tel.: +38 (044)4542079

email: vkondr@gmail.com

https://orcid.org/0000-0002-2506-5009

O. M. Symonov, Shalimov National Institute of Surgery and Transplantology, Kyiv

Oleh Symonov

Surgeon oncologist, Department of combined pathology and retroperitoneal surgery,

Shalimov National Institute of Surgery and Transplantology,

Address: 30 HeroivSevastopolya Str., 03680, Kyiv, Ukraine, tel.: +38 (044)4542079

email: Dr.Simonov84@gmail.com

https://orcid.org/0000-0003-1558-9260

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Published
2018-09-30
How to Cite
Skums, A. V., Gulko, O. M., Kondratiuk, B. A., & Symonov, O. M. (2018). Multidisciplinary approach in surgical treatment of the suprarenal gland pheochromocytoma. Klinicheskaia Khirurgiia, 85(9), 35-38. https://doi.org/10.26779/2522-1396.2018.09.35
Section
General Problems of Surgery