Combined application of cryosurgical method and chemical destruction in complex treatment of patients with focal hepatic pathology


  • O. I. Dronov Bogomolets National Medical University, Kyiv, Kyiv’s Municipal Centre of Surgery of the Diseases of liver, Biliary Ducts and Pancreatic Gland named after V. S. Zemskov https://orcid.org/0000-0003-4033-3195
  • I. O. Kovalska Bogomolets National Medical University, Kyiv, Kyiv’s Municipal Centre of Surgery of the Diseases of liver, Biliary Ducts and Pancreatic Gland named after V. S. Zemskov https://orcid.org/0000-0002-6264-2928
  • Ye. S. Kozachuk Bogomolets National Medical University, Kyiv, https://orcid.org/0000-0002-2453-2496
  • D. I. Khomenko Bogomolets National Medical University, Kyiv https://orcid.org/0000-0002-3911-1088
  • P. P. Bakunets Kyiv’s Municipal Centre of Surgery of the Diseases of liver, Biliary Ducts and Pancreatic Gland named after V. S. Zemskov https://orcid.org/0000-0003-2792-0993
Keywords: cryosurgical method; cryodestruction; chemical destruction; 10% solution of calcium chloridе; focal hepatic pathology

Abstract

Objective. To estimate the efficacy of combined application of cryosurgical method and chemical destruction, using 10% solution of calcium chloride in complex treatment of patients, suffering focal hepatic pathology (FHP).

Маterials and methods. Results of application of local methods of destruction in a content of complex treatment of 316 patients with FHP were analyzed.

Results. Trustworthy difference between the groups of the patients investigated in accordance to rate, structure, severity of specific complications, lethality was not revealed (p > 0.05). After combined application of cryosurgical method and chemical destruction the rate of complete and partial answers of tumoral foci towards the treatment have been trustworthily enhanced, the rate of local recurrence, the process stabilization and progress - diminished (p < 0.05), and the rate of conversion towards resectability enhanced (p < 0.05).

Conclusion. Combined application of cryodestruction and chemical ablation constitutes a secure and effective method, which give possibility to improve the results of treatment in patients with FHP trustworthily.

References

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Author Biographies


O. I. Dronov, Bogomolets National Medical University, Kyiv, Kyiv’s Municipal Centre of Surgery of the Diseases of liver, Biliary Ducts and Pancreatic Gland named after V. S. Zemskov

Dronov O.I. - MD, Doctor of Sci (Med), Professor

Head Of Department Of General Surgery #1

Bogomolets National Medical University

13 Shevchenko avenue, 01004, Kyiv, Ukraine

tel. +38044 234 4062

kafedra1nmu@gmail.com

orcid.org/0000-0003-4033-3195


I. O. Kovalska, Bogomolets National Medical University, Kyiv, Kyiv’s Municipal Centre of Surgery of the Diseases of liver, Biliary Ducts and Pancreatic Gland named after V. S. Zemskov

Kovalska I.O. - MD, Doctor of Sci (Med), Professor

Department Of General Surgery #1

Bogomolets National Medical University

13 Shevchenko avenue, 01004, Kyiv, Ukraine

tel. +38044 234 4062

kafedra1nmu@gmail.com

orcid.org/0000-0002-6264-2928


Ye. S. Kozachuk, Bogomolets National Medical University, Kyiv,

Kozachuk Ye.S. - MD, Assistant Professor

Department Of General Surgery #1

Bogomolets National Medical University

13 Shevchenko avenue, 01004, Kyiv, Ukraine

tel. +38044 234 4062

kafedra1nmu@gmail.com

orcid.org/0000-0002-2453-2496


D. I. Khomenko, Bogomolets National Medical University, Kyiv

Khomenko D.I. - MD, graduate student

Department Of General Surgery #1

13 Shevchenko avenue, 01004, Kyiv, Ukraine

tel. +38044 234 4062

doc.homenko@gmail.com

orcid.org/0000-0002-3911-1088


P. P. Bakunets, Kyiv’s Municipal Centre of Surgery of the Diseases of liver, Biliary Ducts and Pancreatic Gland named after V. S. Zemskov

Bakunets P.P. - MD, PhD (Med)

Kyiv City Center Of Liver, Pancreas And Bile Duct Surgery

13 Shevchenko avenue, 01004, Kyiv, Ukraine

tel. +38044 234 4062

bakunetspetro@gmail.com

orcid.org/0000-0003-2792-0993

Published
2018-10-29
How to Cite
Dronov, O. I., Kovalska, I. O., Kozachuk, Y. S., Khomenko, D. I., & Bakunets, P. P. (2018). Combined application of cryosurgical method and chemical destruction in complex treatment of patients with focal hepatic pathology. Klinicheskaia Khirurgiia, 85(10), 14-16. https://doi.org/10.26779/2522-1396.2018.10.14
Section
General Problems of Surgery