Sarcopenia as a factor of prognosis for development of postoperative complications in patients with pancreatic adenocarcinoma


Keywords: pancreatic tumors; sarcopenia; postoperative complications

Abstract

Objective. Determination of sarcopenia impact on occurrence of complications after pancreatic resections for the organ’s malignancies.

Маterials and methods. There were retrospectively analyzed the treatment results in 87 patients, in whom radical operations were performed. Using preoperative CT, the average value of density was calculated in Hounsfield Units (Hounsfield Unit Average Calculation - HUAC), and a summated Total Psoas Index (TPI) of m. psoas major on the level of the third lumbar vertebra.

Results. In 35 (40.2%) patients a sarcopenia was revealed while applying HUAC index. Postoperative complications have occurred in 21 (60%) patients with sarcopenia, 2 (5.7%) patients died. Postoperative complications have occurred in 16 (30.8%) patients without sarcopenia, 1 (1.9%) patient died. Using a TPI, a sarcopenia was diagnosed in 38 (43.7%) patients, of them the complications have had occurred in 21 (55.3%), and 2 (5.3%) died. Complications have occurred in у 16 (32.6%) patients without sarcopenia, 1 (2.0%) patient died.

Conclusion. Sarcopenia trustworthily impacts the postoperative complications rate, its revealing may be applied for improvement of the patients’ selection before conduction of pancreatic resection for the organ’s malignancies.

References

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doi 10.1186/s12893-017-0261-7.

Author Biographies


V. M. Kopchak, Shalimov National Institute of Surgery and Transplantology, Kyiv

Kopchak Volodymyr, MD, Prof.

Head of the Department of Pancreatic Surgery and Bile Ducts Surgery.

Shalimov National Institute of Surgery and Transplantology,

Heroiiv Sevastopolya 30 st., Kyiv, 03680.

 044 454 20 09.

vmkopchak@gmail.com.

Orcid.org/0000-0003-0134-7500


L. O. Pererva, Shalimov National Institute of Surgery and Transplantology, Kyiv

Pererva Liudmyla, PhD.

Scientific researcher of the Department of Pancreatic Surgery and Bile Ducts Surgery.

Shalimov National Institute of Surgery and Transplantology,

Heroiiv Sevastopolya 30st., Kyiv, 03680.

044 454 20 09.

perervalunet@bigmir.net.

Orcid.org/0000-0002-4030-1030


I. V. Khomiak, Shalimov National Institute of Surgery and Transplantology, Kyiv

Khomyak Ihor, MD, Prof.

Chief researcher of the Department of Pancreatic Surgery and Bile Ducts Surgery.

Shalimov National Institute of Surgery and Transplantology,

Heroiiv Sevastopolya 30st., Kyiv, 03680.

 044 454 20 09.

Md.khomiak@gmail.com.

Orcid.org/0000-0002-3299-7840


O. V. Duvalko, Shalimov National Institute of Surgery and Transplantology, Kyiv

Duvalko Olexandr, PhD.

Senior Researcher of the Department of Pancreatic Surgery and Bile Ducts Surgery.

Shalimov National Institute of Surgery and Transplantology,

Heroiiv Sevastopolya 30st., Kyiv, 03680.

 044 454 20 09.

A.duvalko@gmail.com.

Orcid.org/0000-0001-7423-916X


H. H. Shevkolenko, Shalimov National Institute of Surgery and Transplantology, Kyiv

Shevkolenko Hennadii,

surgeon of the Department of Pancreatic Surgery, Laparoscopic and Surgery of Bile Ducts,

Shalimov National Institute of Surgery and Transplantology,

Heroiiv Sevastopolya 30st., Kyiv, 03680.

044 40818 00.

g.shevkolenko@gmail.com.

Orcid.org/0000-0001-9089-3604


N. G. Davydenko, Shalimov National Institute of Surgery and Transplantology, Kyiv

Davydenko Nina, doctor-anesthesiologist,

head of department of anesthesiology and intensive therapy.

Shalimov National Institute of Surgery and Transplantology,

HeroiivSevastopolya 30st., Kyiv, 03680.

044 40818 00.


K. V. Kopchak, National Cancer Institute, Kyiv

Kopchak Kostiantyn, MD.

Lead researcher of the research department of abdominal tumors.

National Cancer Institute,

Lomonosov 33/43 st., Kyiv, 03022. 044 257 93 15.

kvkopchak@gmail.com.

Orcid.org/0000-0002-9804-4073

Published
2018-10-29
How to Cite
Kopchak, V. M., Pererva, L. O., Khomiak, I. V., Duvalko, O. V., Shevkolenko, H. H., Davydenko, N. G., & Kopchak, K. V. (2018). Sarcopenia as a factor of prognosis for development of postoperative complications in patients with pancreatic adenocarcinoma. Klinicheskaia Khirurgiia, 85(10), 17-20. https://doi.org/10.26779/2522-1396.2018.10.17
Section
General Problems of Surgery

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