Radiological and pathohistological methods of estimation of peripheral segment of the arterial bed for objectivization of the diabetic foot syndrome


Keywords: diabetic macroangiopathy; multidetector computed-tomographic angiography; direct morphometry; atherosclerosis

Abstract

Objective. Enhancing of informativity of multidetector computed-tomographic angiography (MDCTA) and histomorphometry of the lower extremities (LE) vessels, using their comparison and determination of clinical validity, including the patients, suffering a diabetic foot syndrome (DFS).

Materials and methods. There were examined 80 patients (all are men) with DFS, to whom preoperative MDCTA of LE and histomorphometry of vascular structures of postoperative biomaterial were done.

Results. MDCTA have had lower sensitivity (31.3%) vs histological investigation, concerning determination of the atherosclerotic pluck kind as well as in accordance to data about a certain known stage of the beginning or maturing of this named pathomorphological process. There was established, that using MDCTA and a direct morphometry it is possible to gain a highly informative quantitative data on anatomic dimensions of the arteries investigated (the square under the ROC-curve equaled 0.994 and 0.875 accordingly), if to rely on statistically trustworthy results of the diagnostic tests quality in accordance to the experts scale of classificators.

Conclusion. MDCTA has high significance in diagnosis of atherosclerotic plucks, but it may not be regarded a «golden standard» for differentiation of the atherosclerosis stages in patients, suffering diabetic angiopathy. Direct morphometry of arterial structures of the diabetic foot gave away the concerning operating characteristics of MDCTA because of complexity of a process of artificial restoration of the arterial bed hemostasisa, what have impacted the state of the anatomic structures investigated.

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Author Biographies


T. L. Lenchuk, Ivano-Frankivsk National Medical University

Lenchuk Tetiana L., - MD, PhD (Med), Associate Professor

Department of Radiology and Radiation Medicine,

Ivano-Frankivsk National Medical University,

 2 Galytska Str.,76000, Ivano-Frankivsk, Ukraine

+38(0342)528176   

tatyanalenchuk@gmail.com

https://orcid.org/0000-0002-5737-8261


V. M. Matskevych, Ivano-Frankivsk National Medical University

Matskevych Victoriia M. - MD, PhD (Med), Assystent

Department of Radiology and Radiation Medicine,

Ivano-Frankivsk National Medical University,

 2 Galytska Str.,76000, Ivano-Frankivsk, Ukraine

+38(0342)528176   

vikaapo@gmail.com

https://orcid.org/0000-0003-2663-9702


S. M. Vasyliuk, Ivano-Frankivsk National Medical University

Vasyliuk Serhii M. - MD, Doctor of Sci (Med), Professor,

Head of the Surgery Department  #1

 Ivano-Frankivsk National Medical University,

 2 Galytska Str.,76000, Ivano-Frankivsk, Ukraine

+38(0342)537695

surifnmu@gmail.com

https://orcid.org/0000-0002-9434-0377

Published
2018-11-01
How to Cite
Lenchuk, T. L., Matskevych, V. M., & Vasyliuk, S. M. (2018). Radiological and pathohistological methods of estimation of peripheral segment of the arterial bed for objectivization of the diabetic foot syndrome. Klinicheskaia Khirurgiia, 85(11), 44-48. https://doi.org/10.26779/2522-1396.2018.11.44
Section
General Problems of Surgery