Еlastography of a shift wave in estimation of morphological changes in pancreatic gland in chronic pancreatitis

Keywords: pancreatic gland; chronic pancreatitis; fibrosis; inflammation; еlastography of a shift wave; morphology

Abstract

Objective. To establish the sensitivity and specificity of elastography of the shift wave in estimation of morphological changes in pancreatic gland in chronic pancreatitis.

Маterials and methods. Retrospective analysis of the preoperative elastography results, concerning the shift wave, was accomplished, using the morphological investigations data from the pancreatic gland biopsies, оbtained in 68 patients, оperated on for complications of chronic pancreatitis (the main group), and in 30 patients, not owing the chronic pancreatitis signs (control group).

Results. Application of elastographic the shift wave procedure in estimation of morphologic pancreatic changes in chronic pancreatitis made it possible to elaborate a diagnostic pattern of a high quality with sensitivity 80.1% and specificity 86.4%. Morphological changes in the organ in stages of early and late fibrosis on background of active and nonactive inflammation of its parenchyma were verified in accordance to a color pattern and indices of the pancreatic parenchyma rigidity.

Conclusion. The most trustworthy numeral indices of elastography of a shift wave were delineated in noninvasive estimation of the inflammation activity and a stage of the pancreatic fibrous transformation degree in chronic pancreatitis.

Author Biographies

O. M. Babii, Іnstitute of Gastroenterology, Dnipro

Babii Oleksandr M. - MD, DSci (Med)

senior Researcher in Departament of Surgery of Digestive,

Institute of Gastroenterology

Slobozhansky Avenue, 96, 49074, Dnipro, Ukraine

Tel. +380562 27 05 59,

E-mail: aleksandr_babiy@ukr.net

https://orcid.org/0000-0001-7482-684X

B. F. Shevchenko, Іnstitute of Gastroenterology, Dnipro

Shevchenko Boris F. - MD, DSci (Med), Professor,

Chief Researcher in Departament of Surgery of Digestive,

Institute of Gastroenterology

Slobozhansky Avenue, 96, 49074, Dnipro, Ukraine

Tel. +380562 27 05 59,

E-mail: shebef1945@gmail.com

https://orcid.org/0000-0001-9253-4883

I. S. Konenko, Іnstitute of Gastroenterology, Dnipro

Konenko Iryna S.,

Researcher in Departament of Minimally invasive Surgery and Instrumental Diagnostics,

Institute of Gastroenterology

Slobozhansky Avenue, 96, 49074, Dnipro, Ukraine

Tel. +380562 27 59 16,

E-mail: irynakonenko@ukr.net

https://orcid.org/0000-0002-7619-699X

N. G. Gravirovskya, Іnstitute of Gastroenterology, Dnipro

Gravirovskaya Nina G., PhD (Med)

senior Researcher in Departament of Minimally invasive Surgery and Instrumental Diagnostics,

Institute of Gastroenterology

Slobozhansky Avenue, 96, 49074, Dnipro, Ukraine

Tel. +380562 27 59 16,

E-mail: gastro.grav@gmail.com

https://orcid.org/0000-0001-6685-4322

N. Yu. Oshmyanskya, Іnstitute of Gastroenterology, Dnipro

Oshmyanskaya Natalia Y., PhD (Med)

senior Researcher in Departament of Pathomorphology,

Institute of Gastroenterology

Slobozhansky Avenue, 96, 49074, Dnipro, Ukraine

Tel. +380562 27 59 16,

E-mail: betinafei@gmail.com

https://orcid.org/0000-0001-7462-7461

S. V. Ushchina, Іnstitute of Gastroenterology, Dnipro

Ushchina Svitlana V.,

head in Department of Anaesthesiology and Intensive Therapy,

Institute of Gastroenterology

Slobozhansky Avenue, 96, 49074, Dnipro, Ukraine

Tel. +380562 27 05 59,

E-mail: ushchinas@mail.ru

https://orcid.org/0000-0003-2014-1399

References

1. Kawada N, Tanaka S, Uehara H, Takakura R, Katayama K, Fukuda J, et al. Potential use of point shear wave elastography for the pancreas : a single center prospective study. Eur J Radiol. 2014 Apr;83(4):620-4. doi: 10.1016/j.ejrad.2013.11.029. Epub 2013 Dec 27.
2. Ophir J, Céspedes I, Ponnekanti H, Yazdi Y, Li X. Elastography: a quantitative method for imaging the elasticity of biological tissues. Ultrason Imaging. 1991 Apr;13(2):111-34. doi:10.1177/016173469101300201.
3. Dynnyk OB, Zhajvoronok MM, Kobylyak NM, Harchenko MC. Ultrazvukova elastografiya: teoriya i praktyka stvorennya navchalnogo trenazhera. Promeneva diagnostyka, promeneva terapiya. 2014;(3):42-53. [In Ukrainian].
4. Sandrin L, Fourquet B, Hasquenoph JM, Yon S, Fournier C, Mal F, et al. Transient elastography: A new non-invasive method for assessment of hepatic fibrosis. Ultrasound Med Biol. 2003 Dec;29(12):1705-13.
5. Uchida H, Hirooka Y, Itoh A, Kawashima H, Hara K, Nonogaki K, et al. Feasibility of tissue elastography using transcutaneous ultrasonography for the diagnosis of pancreatic diseases. Pancreas. 2009 Jan;38(1):17-22. doi: 10.1097/MPA.0b013e318184db78.
6. Săftoiu A, Vilmann P, Gorunescu F, Janssen J, Hocke M, Larsen M, et al. Accuracy of endoscopic ultrasound elastography used for differential diagnosis of focal pancreatic masses: a multicenter study. Endoscopy. 2011 Jul;43(7):596-603. doi: 10.1055/s-0030-1256314.
7. Park MK, Jo J, Kwon H, Cho JH, Oh JY, Noh MH, et al. Usefulness of acoustic radiation force impulse elastography in the differential diagnosis of benign and malignant solid pancreatic lesions. Ultrasonography. 2014 Jan;33(1):26-33. doi: 10.14366/usg.13017.
8. Kuwahara T, Hirooka Y, Kawashima H, Ohno E, Sugimoto H, Hayashi D, et al. Quantitative evaluation of pancreatic tumor fibrosis using shear wave elastography.. Pancreatology. 2016 Nov-Dec;16(6):1063-1068. doi: 10.1016/j.pan.2016.09.012.
9. Kuwahara T, Hirooka Y, Kawashima H, Ohno E, Ishikawa T, Yamamura T, et al. Usefulness of shear wave elastography as a quantitative diagnosis of chronic pancreatitis. J Gastroenterol Hepatol. 2018 Mar;33(3):756-761. doi: 10.1111/jgh.13926.
10. Gal'perin Je. I. Classification of chronic pancreatitis: determination of severity, choice of method of treatment and necessary operation. Annaly hirurgicheskoy hepatologii. 2013; 18(4):83-92. [In Russian].
11. Barannyk JeO, Lins’ka GV, Dynnyk O B, Marusenko AI. Artefakty ta metodychni pomylky zsuvnohvyl’ovoji elastografiji. Promeneva diagnostyka, promeneva terapiya. 2015;1:61-71. [In Ukrainian].
12. Morgenroth K, Kozuschek W. Pancreatitis. Berlin-New York: Walter de Gruyter; 1991. 120 p.
Published
2019-03-24
How to Cite
Babii, O. M., Shevchenko, B. F., Konenko, I. S., Gravirovskya, N. G., Oshmyanskya, N. Y., & Ushchina, S. V. (2019). Еlastography of a shift wave in estimation of morphological changes in pancreatic gland in chronic pancreatitis. Klinicheskaia Khirurgiia, 86(1), 10-12. https://doi.org/10.26779/2522-1396.2019.01.10
Section
General Problems of Surgery