Мultimodal program «Fast trасk surgery» in the treatment of mammary gland cancer


Keywords: Fast Track Surgery; mammary gland cancer; reconstructive surgery

Abstract

Objective. Improvement of immediate and late results of treatment of mammary gland cancer (MGC), using elaboration and introduction of multimodal program «Fast track surgery» (FTS) in aspect of performance of a one-staged oncoplastic and reconstructive-restoration operations.

Маterials and methods. The treatment results were investigated in 749 patients, suffering MGC Stages T1-4 N0-3 M0 from Dec. 2010 tо Dec. 2014 yr. The patients have aged from 18 tо 70 yrs old. The main group (treatment in accordance to the FTS program) consisted of 253 patients, and a control one – of 496 patients, who were treated in accordance to conventional standards.

Results. The main group patients have been on stationary treatment (14.27 ± 7.00) days at average, and the control one – (20.11 ± 7.70) days of stationary stay at average (p < 0.001). The main group patients, who have had more severe stages of the disease, stayed in stationary by 8 days lesser, comparing with patients of a control group. Average term of the patients’ stationary stay, in whom adjuvant chemotherapy (АCHTH) was performed, have constituted 16.4 days, while in those, in whom АCHTH was conducted, - 20.1 days (р < 0.001). Difference between term of the patients’ stationary stay in the main group, to whom ACHTH was conducted and to whom it was not, was in 2.7 times lesser, comparing with this index in a control group.

Conclusion. The investigation data gives background to recommend a FTS program for wide introduction into medical practice, because its efficacy in the MGC surgery was confirmed, including the one-staged oncoplastic and reconstructive-restoration operations. Gradual shortening of the stationary treatment duration gave possibility from 2008 tо 2018 years to enhance the operated patients quantity by 75%.

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Author Biographies


I. M. Motuziuk, Bogomolets National Medical University, Kyiv

Ihor Motuziuk – MD, PhD (Med), Assistant Professor,
Oncology Department,
Bogomolets National Medical University
03022, 33/43 Lomonosova Str., Kyiv, Ukraine
cell: +38 067 719 99 22,
e-mail: 180978igor@gmail.com
https://orcid.org/0000-0002-8332-3280


O. I. Sydorchuk, Bogomolets National Medical University, Kyiv

Oleg Sydorchuk – MD, PhD (Med), Associate Professor,
Oncology Department,
Bogomolets National Medical University
03022, 33/43 Lomonosova Str., Kyiv, Ukraine
cell: +38 097 371 85 76,
e-mail: oleg.sydorchuk0@gmail.com
https://orcid.org/0000-0002-6209-1353


E. V. Kostiuchenko, Bogomolets National Medical University, Kyiv

Yevhenii Kostiuchenko – MD, PhD (Med) Student, Assistant Professor, Yevhenii Kostiuchenko – MD, PhD (Med) Student, Assistant Professor, Oncology Department, Bogomolets National Medical University 03022, 33/43 Lomonosova Str., Kyiv, Ukrainecell: +38 099 282 62 73, e-mail: yekostiuchenko@gmail.comhttps://orcid.org/0000-0001-9218-0050


N. V. Kovtun, LLC Chiltern Clinical Research Ukraine, Kyiv, Taras Shevchenko National University, Кyiv

Natalia Kovtun – DSc (ECON), Professor,
Department of Statistics and Demography,
Taras Shevchenko National University of Kyiv
03022, 90-A Vasylkivska Str., Kyiv, Ukraine
cell: +38 063 383 73 00,
e-mail: kovtun_natali@ukr.net
https://orcid.org/0000-0002-2935-8597


P. L. Poniatovskyi, Bogomolets National Medical University, Kyiv

Petro Poniatovskyi – Medical student, Petro Poniatovskyi – Medical student, Oncology DepartmentBogomolets National Medical University 03022, 33/43 Lomonosova Str., Kyiv, Ukrainecell: +38 067 311 80 55, e-mail: poniatovskyi.petro@gmail.comhttps://orcid.org/0000-0002-0047-6928

Published
2019-02-27
How to Cite
Motuziuk, I. M., Sydorchuk, O. I., Kostiuchenko, E. V., Kovtun, N. V., & Poniatovskyi, P. L. (2019). Мultimodal program «Fast trасk surgery» in the treatment of mammary gland cancer. Klinicheskaia Khirurgiia, 86(2), 43-48. https://doi.org/10.26779/2522-1396.2019.02.43
Section
General Problems of Surgery