Application of the diffusion-weighted images of the magnet-resonance tomography for prognostication of course of chronic renal disease in patients, suffering reno-cellular cancer after renal resection
Objective. To study the possibility of application of the diffusion-weighted images of the magnet resonance tomography (МRТ) for prognostication of the chronic renal disease (CHRD) development in the patients, suffering renal-cellular cancer (RCC) after renal resection.
Маterials and methods. In the investigation 44 patients, distributed into two groups, took part: in Group I (main) 24 patients were included, in whom for the first time a RCC was diagnosed in stages Т1аN0M0G1-G3, and Group II (control) - 20 patients without signs of RCC and disorders of аnatomic-functional state of the kidneys.
Results. Lowering of a measurable diffusion coefficient (MDC) іn intact part of cortex in the oncologically affected kidney on the diffusion-weighted images of МRТ in comparison with the MDC values of a normal renal cortex have served as a prognostic marker of lowering of velocity in glomerular filtration on ipsilateral side, what may be regarded as a condition for the CHRD development.Conclusion. Calculation of MDC on the diffusion-weighted images of MRT makes possible to prognosticate the lowering of the functional capacity of kidney, effected by the tumor, in the patients, suffering RCC stage T1а after its resection, what is significant for metaprophylaxis of the CHRD development in this patients.
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