Chronic pancreatitis and diabetes mellitus - predictors of development of pancreatic cancer

Abstract

Chronic pancreatitis and diabetes mellitus - predictors of development of pancreatic cancer

Author Biographies

A. I. Sukhodolia, Pyrogov National Medical University, Vinnytsya, Khmelnytskyi Regional Hospital

Sukhodolia Anatolii Ivanovych DMedSc prof.,
Head of the Department of Surgery FPE of Doctors
Pirogov National Medical University, Vinnytsya.
Khmelnytskyi Regional Clinical Hospital, Pilotska str 1.
asukhodolia@gmail.com
tel 067 661 65 03
https://orcid.org/0000-0002-5784-703X

S. A. Sukhodolia, Khmelnytskyi Regional Hospital

Sukhodolia Sergii, PhD, surgeon
Khmelnitsky regional hospital,
Pilotska str 1 ssukhodolia@gmail.com
tel 097 93 98 537
https://orcid.org/0000-0002-5784-703X

V. P. Mosiychuk, Pyrogov National Medical University, Vinnytsya, Khmelnytskyi Regional Hospital

Mosiychuk Vasyl Petrovych
clinic. resident
Department of Surgery with the Course of Stomatology of the FPE
Pirogov National Medical University, Vinnytsya.
Khmelnytskyi Regional Clinical Hospital,
Pilotska str 1.
tel.+ 38097 506 75 41
Vasiliymosiichuk@gmail.com
https://orcid.org/0000-0001-7909-131X

M. V. Makohonskyi, Pyrogov National Medical University, Vinnytsya, Khmelnytskyi Regional Hospital

Makohonskyi Mykola Vitaliiovych, intern
Department of Surgery with the Course of Stomatology of the FPE
Pirogov National Medical University, Vinnytsya.
Khmelnytskyi Regional Clinical Hospital,
Pilotska str 1. tel. 096 534 01 62.
Makohonskyi@gmail.com
https://orcid.org/0000-0002-4195-9731

References

1. Maisonneuve P, Lowenfels AB. Risk factors for pancreatic cancer: a summary review of meta-analytical studies. Int J Epidemiol. 2015 Feb;44(1):186-98. doi: 10.1093/ije/dyu240.
2. Hao L, Zeng XP, Xin L, Wang D, Pan J, Bi YW, et al. Incidence of and risk factors for pancreatic cancer in chronic pancreatitis: A cohort of 1656 patients. Dig Liver Dis. 2017 Nov;49(11):1249-56. doi: 10.1016/j.dld.2017.07.001.
3. Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho R.A. Genetics and biology of pancreatic ductal adenocarcinoma. Genes and Development. 2006 May 15;20(10):1218-49. doi: 10.1101/gad.1415606.
4. Rooman I, Real FX. Pancreatic ductal adenocarcinoma and acinar cells: a matter of differentiation and development? Gut. 2012 Mar;61(3):449-58. doi: 10.1136/gut.2010.235804.
5. Sandgren EP, Quaife CJ, Paulovich AG, Palmiter RD, Brinster RL. Pancreatic tumor pathogenesis reflects the causative genetic lesion. Proceedings of the National Academy of Sciences of the United States of America. 1991 Jan 1;88(1):93-7. PMID: 1986386.
6. Kirkegaard J, Mortensen FV, Cronin-Fenton D. Chronic Pancreatitis and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis. Am J Gastroenterol. 2017 Sep;112(9):1366-72. doi: 10.1038/ajg.2017.218.
7. Warshaw AL, Fernandez-Del Castillo C. Pancreatic carcinoma. N Engl J Med. 1992 Feb 13;326(7):455-65. doi: 10.1056/nejm199202133260706.
8. Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015 Mar 1;136(5):359-86. doi: 10.1002/ijc.29210.
9. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global Cancer Statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018 Nov;68(6):394-424. doi: 10.3322/caac.21492.
10. Muniraj T, Jamidar PA, Aslanian HR. Pancreatic cancer: a comprehensive review and update. Dis Mon. 2013 Nov;59(11):368-402. doi: 10.1016/j.disamonth.2013.08.001.
11. Ilic M, Ilic I. Epidemiology of pancreatic cancer. World J Gastroenterol. 2016 Nov 28;22(44): 9694-705. doi:10.3748/wjg.v22.i44.9694.
12. Kopchak V, Homyak I, Kopchak K, Duvalko A, Pererva L, Simonov O, et al. Radical surgical treatment of malignant periampullar neoplasms. Klinicheskaya onkologia. 2011;(1):36-9. [In Russian].
13. Kikuyama M, Kamisawa T, Kuruma S, Chiba K, Kawaguchi S, Terada S, et al. Early Diagnosis to Improve the Poor Prognosis of Pancreatic Cancer. Cancers. 2018 Feb 11;10(2):48. doi:10.3390/cancers10020048.
14. Kanno A, Masamune A, Hanada K, Maguchi H, Shimizu Y, Ueki T, et al. Multicenter study of early pancreatic cancer in Japan. Pancreatology. 2018 Jan;18(1):61-7. doi: 10.1016/j.pan.2017.11.007.
15. Yokode M, Akita M, Fujikura K, Kim MJ, Morinaga Y, Yoshikawa S, et al. High-grade PanIN presenting with localized stricture of the main pancreatic duct: A clinicopathological and molecular study of 10 cases suggests a clue for the early detection of pancreatic cancer. Histopathology. 2018 Aug;73(2):247-58. doi: 10.1111/his.13629.
16. Fernandez E, La Vecchia C, Porta M, Negri E, d’Avanzo B, Boyle P. Pancreatitis and the risk of pancreatic cancer. Pancreas. 1995 Aug;11(2):185-9. PMID: 7479677.
17. Lowenfels, AB, Maisonneuve P, Cavallini G, Ammann RW, Lankisch PG, Andersen JR, et al. Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. N Engl J Med. 1993 May 20;328(20):1433-7. doi: 10.1007/s10552-009-9424-x.
18. Sukhodolia A, Pidmurnyak O, Sukhodolia S, Troparchuk O, Kolomiets O. Diagnostics and Identification of surgical treatment tactics of complicated forms of chronic pancreatitis. Shpytalna khirurhiia. 2016;(3):53-6. [In Ukrainian].
19. Virchow R. The Cellular Pathology. 4th ed. Berlin: Hirschwald; 1871. 582 р.
20. Greer JB, Whitcomb DC. Inflammation and pancreatic cancer: an evidence-based review. Curr Opin Pharmacol. 2009 Aug;9(4):411-8. doi: 10.1016/j.coph.2009.06.011.
21. Karanjia ND, Singh SM, Widdison AL, Lutrin FJ, Reber HA. Pancreatic ductal and interstitial pressure in cats with chronic pancreatitis. Dig Dis Sci. 1992 Feb;37(2):268-73. PMID: 1735346.
22. Whatcott CJ, Diep CH, Jiang P, Watanabe A, LoBello J, Sima C, et al. Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer. Clin Cancer Res. 2015 Aug 1;21(15):3561-8. doi: 10.1158/1078-0432.CCR-14-1051.
23. Kirkegaard J, Mortensen FV, Cronin-Fenton D. Chronic Pancreatitis and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis. Am J Gastroenterol. 2017 Sep;112(9):1366-72. doi: 10.1038/ajg.2017.218.
24. Rijkers AP, Bakker OJ, Ahmed Ali U, Hagenaars JCJP, van Santvoort HC, Besselink MG, et al. Risk of Pancreatic Cancer After a Primary Episode of Acute Pancreatitis. Pancreas. 2017 Sep;46(8):1018-22. doi: 10.1097/MPA.0000000000000879.
25. Javier Martinez-Useros, Weiyao Li, Marticela Cabeza-Morales, Jesus Garcia-Foncillas. Oxidative Stress: A New Target for Pancreatic Cancer Prognosis and Treatment. J Clin Med. 2017 Mar; 6(3):29. doi:10.3390/jcm6030029.
26. Yu JH, Kim H. Oxidative stress and cytokines in the pathogenesis of pancreatic cancer. J Cancer Prev. 2014 Jun;19(2):97-102. doi: 10.15430/JCP.2014.19.2.97.
27. Dronov OI, Kryuchyna YeA, Khomenko DI, Skomarovsky OA, Gorlach AI, Zemskov SV, et al. Chronic pancreatitis as a risk factor of pancreatic cancer development. Khirurhiia Ukrainy. 2013 Sept; 47(3):112-6.[In Russian].
28. Okami J, Yamamoto H, Fujiwara Y, Tsujie M, Kondo M, Noura S, et al. Overexpression of cyclooxygenase-2 in carcinoma of the pancreas. Monden M Clin Cancer Res. 1999 Aug;5(8):2018-24. PMID: 10473081.
29. Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N, Perucho M. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell. 1988 May 20;53(4):549-54. PMID: 2453289.
30. Pellegata NS, Sessa F, Renault B, Bonato M, Leone BE, Solcia E, et al. K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions. Cancer Res. 1994 Mar 15;54(6):1556-60. PMID: 8137263.
31. Bryant KL, Mancias JD, Kimmelman AC, Der CJ. KRAS: Feeding pancreatic cancer proliferation. Trends Biochem Sci. 2014 Feb;39(2):91-100. doi: 10.1016/j.tibs.2013.12.004.
32. Lohr M1, Kloppel G, Maisonneuve P, Lowenfels AB, Luttges J. Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: a meta-analysis. Neoplasia. 2005 Jan;7(1):17-23. doi: 10.1593/neo.04445.
33. Wang X, Wang J, Chen F, Zhong Z, Qi L. Detection of K-ras gene mutations in feces by magnetic nanoprobe in patients with pancreatic cancer: A preliminary study. Exp Ther Med. 2018 Jan;15(1):527-31. doi: 10.3892/etm.2017.5368.
34. Sarkar FH, Banerjee S, Li Y. Pancreatic cancer: pathogenesis, prevention and treatment. Toxicol Appl Pharmacol. 2007 Nov 1;224(3):326-36. doi: 10.1016/j.taap.2006.11.007.
35. Dankner R, Freedman LS, Gerstein H, Roth J, Keinan-Boker L. Newly diagnosed type 2 diabetes may serve as a potential marker for pancreatic cancer. Diabetes/Metabolism Research and Reviews. 2018 Sept;34(6). doi: 10.1002/dmrr.3018.
36. IDF diabetes atlas - eight edition [Internet]. 2017. Available from: https://www.idf.org/e-library/epidemiology-research/diabetes-atlas/134-idf-diabetes-atlas-8th-edition.html
37. Heidemann C, Boeing H, Pischon T, Nothlings U, Joost HG, Schulze MB, et al. Association of a diabetes risk score with risk of myocardial infarction, stroke, specific types of cancer, and mortality: a prospective study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam cohort. Eur J Epidemiol. 2009;24(6):281-8. doi: 10.1007/s10654-009-9338-7.
38. Permert J, Ihse I, Jorfeldt L, von Schenck H, Arnqvist HJ, Larsson J. Pancreatic cancer is associated with impaired glucose metabolism. Eur J Surg. 1993 Feb;159(2):101-7. PMID: 8098623.
39. Jeon CY, Li D, Cleary S, Stolzenberg-Solomon R, Bosetti C, La Vecchia C, et al. The Association of Recently Diagnosed Diabetes and Long-term Diabetes With Survival in Pancreatic Cancer Patients: A Pooled Analysis. Pancreas. 2018 Mar;47(3):314-20. doi: 10.1097/MPA.0000000000000989.
40. Chari ST, Leibson CL, Rabe KG, Timmons LJ, Ransom J, Andrade M, Petersen GM. Pancreatic Cancer-associated Diabetes Mellitus: Prevalence and Temporal Association with Diagnosis of Cancer. Gastroenterology. 2008 Jan;134(1):95-101. doi: 10.1053/j.gastro.2007.10.040.
41. Pannala R, Basu A, Petersen GM, Chari ST. New-onset diabetes: a potential clue to the early diagnosis of pancreatic cancer. Lancet Oncol. 2009 Jan;10(1):88-95. doi: 10.1016/S1470-2045(08)70337-1.
42. Sadr-Azodi O, Gudbjornsdottir S, Ljung R. Pattern of increasing HbA1c levels in patients with diabetes mellitus before clinical detection of pancreatic cancer - a population-based nationwide case-control study. Acta Oncol. 2015 Jul;54(7):986-92. doi: 10.3109/0284186X.2015.1006402.
43. Smith CD, Behrns KE, van Heerden JA, Sarr MG. Radical pancreatoduodenectomy for misdiagnosed pancreatic mass. Br J Surg 1994;81:585-9. PMID: 7911387.
44. Wiersema MJ, Vilmann P, Giovannini M, Chang KJ, Wiersema LM. Endosonography-guided fine-needle aspiration biopsy: diagnostic accuracy and complication assessment. Gastroenterology. 1997 Apr;112(4):1087-95. PMID: 9097990.
45. Perumal S, Palaniappan R, Pillai SA, Velayutham V, Sathyanesan J. Predictors of malignancy in chronic calcific pancreatitis with head mass. World J Gastrointest Surg. 2013 Apr 27;5(4):97-103. doi: 10.4240/wjgs.v5.i4.97.
46. Klimenko A. Importance of onomarker CA 19-9 in diagnostics of chronic pancreatitis. Zaporozhye Medical Journal. 2013;(1):29-31. doi.org/10.14739/2310-1210.2013.1.15450. [In Ukrainian].
47. Kim J, Bamlet WR, Oberg AL, Chaffee KG, Donahue G, Cao XJ, et al. Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers. Sci Transl Med. 2017 Jul 12;398(9):55-83. doi: 10.1126/scitranslmed.aah5583.
48. Park JY, Helm J, Coppola D, Kim D, Malafa M, Kim SJ. MicroRNAs in pancreatic ductal adenocarcinoma. World J Gastroenterol. 2011 Feb 21;17(7):817-27. doi: 10.3748/wjg.v17.i7.817.
Published
2019-06-12
How to Cite
Sukhodolia, A. I., Sukhodolia, S. A., Mosiychuk, V. P., & Makohonskyi, M. V. (2019). Chronic pancreatitis and diabetes mellitus - predictors of development of pancreatic cancer. Klinicheskaia Khirurgiia, 86(4), 67-71. https://doi.org/10.26779/2522-1396.2019.04.67