Investigation of impact of the tissue growth factor and electromagnet irradiation of a light diapason on the small bowel anastomoses in experiment

Keywords: the small intestine anastomosis; insufficiency of anastomosis; phototherapy; the tissue factors of growth; experiment

Abstract

Objective. Elaboration of method for hermetization of sutures of the small bowel anastomosis in conditions of peritonitis.

Materials and methods. The experiment was performed on 20 white male rats of a Wistar line owing a body mass approximately 250 g. The protocol for the laboratory animals care, the content and methods of experimental work were corresponded to principles of European Convention for defense of a vertebrate animals, which are used for research and scientific purposes (Strasbourg, 1986).

Results. The experimental investigation conduction have shown the possibilities of application of physical (the light waves of a certain length) and biological (the tissue growth factors) methods in prophylaxis and treatment of an acute inflammatory reactions and for stimulation of reparative processes.

Conclusion. The trend for further investigation of prophylactic measures for the small bowel anastomoses insufficiency, using the electro–magnet impact of the low–intense of the light spectrum in combination with application of the tissue growth factors, demonstrate a perspective.

Author Biographies

M. E. Tymchenko, Zaytsev Institute of General and Urgent Surgery, Kharkiv, Ukraine

Tymchenko Mykhailo,
Researcher of the Department of comprehensive programming for the development,
Zaycev Institute of General and Urgent Surgery,
1 Balakirev entry, 61018, Kharkov, Ukraine;
tel.: +380504000832;
е-mail: michael.timchenko@gmail.com;
ORCID ID: 0000-0001-8876-5339

Yu. V. Ivanova, Zaytsev Institute of General and Urgent Surgery, Kharkiv, Ukraine

Ivanova Julia – MD, DSci(Med), Principal Research Scientist,
Department of surgical infections,
Zaycev Institute of General and Urgent Surgery,
1 Balakirev entry, 61018, Kharkov, Ukraine;
Kharkov National Medical University;
tel.: 057-349-41-94;
е-mail: dr.ivanova23@gmail.com;
ORCID ID: 0000-0001-8773-6827

O. M. Klimova, Zaytsev Institute of General and Urgent Surgery, Kharkiv, Ukraine

Klimova Elena Mikhaylovna,
Head of the diagnostic laboratory with ELISA and immunofluorescence analysis,
Zaycev Institute of General and Urgent Surgery,
1 Balakirev entry, 61018, Kharkov, Ukraine;
tel.: +380503033172;
е-mail: klimovalena53@gmail.com;
ORCID ID: 0000-0002-4007-6806

O. I. Shchur, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine

Shchur Olha,
Associate Professor,
Department of Anestesiology, Intensive Care, Transfusiology and Hematology,
Kharkov Medical Academy of Postgraduate Education, Kharkiv, Ukraine;
tel.: +38095 734 46 44;
е-mail: olgashyr2017@gmail.com;
ORCID ID: 0000-0002-1241-9314

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Published
2019-09-28
How to Cite
Tymchenko, M. E., Ivanova, Y. V., Klimova, O. M., & Shchur, O. I. (2019). Investigation of impact of the tissue growth factor and electromagnet irradiation of a light diapason on the small bowel anastomoses in experiment. Klinicheskaia Khirurgiia, 86(9), 54-58. https://doi.org/10.26779/2522-1396.2019.09.54
Section
Experimental Investigations