Results of the alcohol septal ablation in combination with simultaneous endoprosthesis of coronary arteries in treatment of patients, suffering obstructive hypertrophic cardiomyopathy and concurrent ischemic heart disease

Keywords: hypertrophic cardiomyopathy; gradient of systolic pressure; the alcohol septal ablation; endoprosthesis of coronary arteries

Abstract

Objective. To study the immediate and remote follow-up results of treatment in patients, suffering obstructive hypertrophic cardiomyopathy and concurrent ischemic heart disease, using the alcohol septal ablation in combination with simultaneous endoprosthesis of coronary arteries.

Materials and methods. In the investigation were included 129 patients, suffering obstructive hypertrophic cardiomyopathy, to whom the alcohol septal ablation was performed in 2009 - 2018 yrs in M. M. Amosov National Institute of Cardiovascular Surgery. All the patients were distributed into two groups: the first -14 (10.9%) patients with concurrent ischemic heart disease and the second -115 (89.1%) patients without concurrent ischemic heart disease.

Results. Reduction of the systolic pressure gradient in the exit tract of the left ventriculus, mitral regurgitation, and the functional class characteristic in accordance to criteria of a New-York Association of Cardiologists in both groups in immediate and late periods of observation have appeared statistically proved. In a remote period of follow-up in 13 (92.9%) patients, suffering the ischemic heart disease, a satisfactory hemodynamical result was registered, and in 1 (7.1%) - poor. Conditionally poor results in this group of patients were absent. The patients without an ischemic heart disease (n=107) in accordance to the above mentioned indices were distributed in a follow manner: 74 (69.2%), 28 (26.2%) and 5 (4.7%), accordingly. Statistically significant difference in accordance to hemodynamical results between two groups of patients was absent in immediate and remote periods of follow-up.

Conclusion. Simultaneous conduction of the alcohol septal ablation in combination with endoprosthesis of coronary arteries in patients, suffering obstructive hypertrophic cardiomyopathy and concurrent ischemic heart disease, constitutes a safe proved combined intervention procedure, which owes good immediate results, persisting in the remote period.

Author Biographies

K. V. Rudenko, M. M. Amosov National Institute of Cardiovascular Surgery, Kyiv

Kostiantyn Rudenko, DSci(Med), professor,
Deputy Director
M. M. Amosov National Institute of Cardiovascular Surgery
Ukraine, Kyiv, 6, M. Amosov str., 03038.
+380 44 333 84 08
kostyantyn.rudenko@gmail.com
ORCID: https://orcid.org/0000-0003-0515-3295

L. O. Nevmerzhytska, M. M. Amosov National Institute of Cardiovascular Surgery, Kyiv

Lidiia Nevmerzhytska, master of medicine, Junior Research Fellow
M. M. Amosov National Institute of Cardiovascular Surgery
Ukraine, Kyiv, 6, M. Amosov str., 03038.
+380 44 333 84 08
lndoc08@gmail.com
ORCID: https://orcid.org/0000-0002-6232-4225

O. Yu. Dudnyk, M. M. Amosov National Institute of Cardiovascular Surgery, Kyiv

Oleksandra Dudnyk, Internist
M. M. Amosov National Institute of Cardiovascular Surgery
Ukraine, Kyiv, 6, M. Amosov str., 03038.
+380 44 333 84 08
sasha.dudnyk@gmail.com
ORCID: https://orcid.org/0000-0002-7748-5726

S. M. Fanta, M. M. Amosov National Institute of Cardiovascular Surgery, Kyiv

Stanislav Fanta, master of medicine, Surgeon
M. M. Amosov National Institute of Cardiovascular Surgery
Ukraine, Kyiv, 6, M. Amosov str., 03038.
+380 44 333 84 08
fantastanislav@gmail.com
ORCID: https://orcid.org/0000-0003-0712-8157

V. V. Lazoryshynets, M. M. Amosov National Institute of Cardiovascular Surgery, Kyiv

Vasyl Lazoryshynets, DSci(Med), Professor
Chief M. M. Amosov National Institute of Cardiovascular Surgery
Ukraine, Kyiv, 6, M. Amosov str., 03038.
+380 44 333 84 08
lazorch@gmail.com
https://orcid.org/0000-0003-0515-3295

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Published
2019-12-20
How to Cite
Rudenko, K. V., Nevmerzhytska, L. O., Dudnyk, O. Y., Fanta, S. M., & Lazoryshynets, V. V. (2019). Results of the alcohol septal ablation in combination with simultaneous endoprosthesis of coronary arteries in treatment of patients, suffering obstructive hypertrophic cardiomyopathy and concurrent ischemic heart disease. Klinicheskaia Khirurgiia, 86(11-12), 3-8. https://doi.org/10.26779/2522-1396.2019.11-12.03
Section
General Problems of Surgery