Prophylaxis of complications after radical operations in patients, suffering a mammary gland cancer

Keywords: mammary gland cancer; operative treatment; postoperative complications; prophylaxis


Objective. Elaboration of prophylactic measures for complications after radical operations in patients, suffering mammary gland cancer, and estimation of its efficacy.

Materials and methods. Immediate results of surgical treatment were analyzed in 147 patients, suffering mammary gland cancer, and distributed, depending on perioperative treatment methods, into: the1st (comparison group) - 92 women-patients, to whom a standard treatment was applied, the second one (main group) - 55 women-patients, in whom complex of prophylactic measures was applied, including organizational, as well as compressive and medicinal therapy.

Results. Application of complex of prophylactic measures was accompanied by reduction of the development rate of postoperative oedema from 50% (comparison group) to 25% (p=0.003), the seroma’s formation - from 29 to 11% (p=0.010), development and severity of postmastectomy syndrome, lymphorrhea - from 29 to 18% (p=0,131) and the wounds complications - from 25 to 7.3% (p=0.007).

Conclusion. After radical operations with the lymph node dissection in patients, suffering mammary gland cancer, the early morbidity rate is rather high, and mainly connected with lymphovenous drainage outflow. The complex of measures, aiming at minimization of the patients’ stationary stay, early extraction of draining tubes, early activation of the patients, the improved compressive and medicinal therapy permits to reduce the rate and severity of morbidity and to accelerate the patients’ recovery and reconvalescence.

Author Biographies

Yu. O. Vinnyk, Kharkiv Medical Academy of Postgraduate Education

Yuri Vinnуk -MD, Doctor of Sci (Med), Professor
Department of cancer surgery, radiation therapy and palliative care
Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
58, Amosova str ., Kharkiv, Ukraine, 61168

V. G. Vlasenko, Medical Centre «Molecula», Kharkiv

Vadym Vlasenko - PhD in Medical sciences;
Department of cancer surgery
Medical Center “Molecule”
7, Hoholya str ., Kharkiv, Ukraine 61057
ORCID: 0000-0002-8215-1958.

A. V. Baranova, Institute of Medical radiology named after S. P. Grygoryev, Kharkiv

Anna Baranova
Department of cancer surgery, radiation therapy and palliative care
Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
58, Amosova str., Kharkiv, Ukraine, 61168
Grigoriev Institute for medical Radiology, Kharkiv
82, Pushkinska Str., Kharkiv, 61024, Ukraine
ORCID: 0000-0002-2419-9910.


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How to Cite
Vinnyk, Y. O., Vlasenko, V. G., & Baranova, A. V. (2019). Prophylaxis of complications after radical operations in patients, suffering a mammary gland cancer. Klinicheskaia Khirurgiia, 86(11-12), 46-50.
General Problems of Surgery