Quality of life in patients, suffering localized reno-cellular cancer after operative treatment

Keywords: reno-cellular cancer; renal resection; nephrectomy; quality of life

Abstract

Objective. To rise the efficacy of treatment in patients, suffering localized reno-cellular cancer (LRCC), studying quality of life in patients and determination of optimal procedure of operative treatment.

Materials and methods. Of 511 patients, suffering LRCC (T1-T2 N0M0), in whom quality of life was estimated in accordance to the SF-36 questionnaire, renal resection  was performed in 422 (82.6%), nephrectomy - 89 (17.4%). The observation duration median have constituted 28.9 mo (from 3 to 131 mo).

Results. A patient’s cognition of the oncological disease missing have raised the quality of life self-estimation, predominantly in accordance to indices of psychological component of health after nephrectomy and after renal resection. Comparing the quality of life between the patients’ groups, there was obtained a statistically significant advantage of renal resection over nephrectomy in accordance to five indices of quality of life, including: physical functioning - 75 [65; 85] points after nephrectomy and 80 [70; 90] points after renal resection (p < 0.005); general state of health - 65 [57; 72] and 70 [65; 80] (p < 0.001); vital activity - 65 [55; 70] and 70 [60; 75] (p < 0.005); psychological health - 76 [60; 80] and 80 [68; 88] (p < 0.005); the emotionally-role functioning - 66.7 [66.7; 100] and 100 [66,7; 100] (p < 0.05) points, accordingly.

Conclusion. Renal resection has a statistically proven advantage over nephrectomy in accordance to patients’ quality of life, determined, basing on data from the SF-36 questionnaire, predominantly due to better psychological self estimation of the patient’s state of health (p < 0.01). Difference between the investigated groups in accordance to indices of pain intensity, social and physical-role functioning was not established.

Author Biographies

O. A. Voylenko, National Cancer Institute, Kyiv

Voylenko Oleg A. - MD, PhD (Med),
Senior Researcher of Department of Plastic and Reconstructive Oncological Urology,
National Cancer Institute,
33/43 Lomonosova Str., 03022, Kyiv, Ukraine
+38 050 501 19 03
voilenko@rambler.ru
orcid.org/0000-0003-3781-3622

O. A. Kononenko, National Cancer Institute, Kyiv

Kononenko Oleksii A. - MD, PhD (Med),
Researcher of Department of Plastic and Reconstructive Oncological Urology,
National Cancer Institute,
33/43 Lomonosova Str., 03022, Kyiv, Ukraine
+38 097 269 32 35
kononenko_ol@ukr.net
orcid.org/0000-0002-7081-5964

S. L. Semko, National Cancer Institute, Kyiv

Semko Sofiya L. - MD,
Urologist of Department of Plastic and Reconstructive Oncological Urology,
National Cancer Institute,
33/43 Lomonosova Str., 03022, Kyiv, Ukraine
+38 063 252 65 36
semkosofiya@gmail.com
orcid.org/0000-0002-1657-5752

M. V. Pikul, National Cancer Institute, Kyiv

Pikul Maksym V. - MD,
Urologist of Department of Plastic and Reconstructive Oncological Urology,
National Cancer Institute,
33/43 Lomonosova Str., 03022, Kyiv, Ukraine
+38 093205 06 96
urogenetics@gmail.com
orcid.org/0000-0003-1590-235X

O. E. Stakhovskyi, National Cancer Institute, Kyiv

Stakhovskyi Oleksandr E. - MD, PhD (Med),
Senior Researcher of Department of Plastic and Reconstructive Oncological Urology,
National Cancer Institute,
33/43 Lomonosova Str., 03022, Kyiv, Ukraine
+38 050 381 72 17
stakhovsky9@gmail.com
orcid.org/0000-0002-0030-5459

Yu. V. Vitruk, National Cancer Institute, Kyiv

Vitruk Iurii V. - MD, PhD (Med),
Senior Researcher of Department of Plastic and Reconstructive Oncological Urology,
National Cancer Institute,
33/43 Lomonosova Str., 03022, Kyiv, Ukraine
+38 050 673 20 82
uvitruk@ukr.net
orcid.org/0000-0003-3466-0552

E. O. Stakhovsky, National Cancer Institute, Kyiv

Stakhovsky Eduard O. - MD, DSci (Med), Professor,
Head of Department of Plastic and Reconstructive Oncological Urology,
National Cancer Institute,
33/43 Lomonosova Str., 03022, Kyiv, Ukraine
+38 067 236 51 75
estakhovsky@yahoo.com
orcid.org/0000-0001-5677-8768

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Published
2019-12-20
How to Cite
Voylenko, O. A., Kononenko, O. A., Semko, S. L., Pikul, M. V., Stakhovskyi, O. E., Vitruk, Y. V., & Stakhovsky, E. O. (2019). Quality of life in patients, suffering localized reno-cellular cancer after operative treatment. Klinicheskaia Khirurgiia, 86(11-12), 56-62. https://doi.org/10.26779/2522-1396.2019.11-12.56
Section
General Problems of Surgery