Investigation of the functional state changes of cardio-vascular system in patients, suffering peritonitis

Keywords: peritonitis; abdominal sepsis; myocardium; electrocardiogram; cardio-vascular insufficiency.

Abstract

Objective. To study a functional state of cardio-vascular system in patients, suffering peritonitis.

Materials and methods. Analysis of dynamics in the electrocardiogram changes in 166 patients, including 84 women and 82 men, was conducted for studying of functional state of cardio-vascular system in extended peritonitis.

Results. Changes on electrocardiograms were non monotonous and depended on the peritonitis stage. In 28.3% patients diffuse changes in myocardium were observed, while in 43.9% - moderate. In 42.6% patients the disorders in metabolic processes in myocardium were revealed. Changes in conductivity and excitability were noted merely in half of the patients. Hypoxia was observed in 17.7% patients in reactive stage of peritonitis, in 32.0% - in a toxic, in 75.8% - in terminal. Tachycardia in a reactive stage of peritonitis was noted in 77.4% patients, in toxic one - in 89.3%, and in terminal - in 86.2% patients. In terminal stage of peritonitis in 13.8% patients bradycardia was noted. The blood supply disorders of various compartments of myocardium was revealed in 34.4% patients.

Conclusion. Functional changes of cardio-vascular system in patients depends on stage of peritonitis. In all the patients, suffering peritonitis, medicinal correction of the cardio-vascular system work must be conducted, while its intensity depends on stage of peritonitis.

Author Biographies

O. O. Bilyayeva, Shupik National Medical Academy of Postgraduate Education, Kyiv

Bilyayeva Olga - MD, DSci, Full Professor
Department of General and Emergency Surgery
Shupyk National University of Health of Ukraine, Kiev, Ukraine
3 L. Husara, Kyiv, 03126.
+38 (044) 497-03-72; 063-243-88-27; 050-702-15-12
pr.bilyayeva@gmail.com
0000-0003-2862-0423

I. V. Karol, Brovary Multidisciplinary Clinical Hospital

Karol Ivan - MD, PhD, Surgeon, surgeon-oncologist
Brovary Multidisciplinary Clinical Hospital
14 Shevchenka Str., Brovary, 07400.
+38 (04594) 4-41-55; 096-652-68-93
drkarol@ukr.net
0000-0003-3684-0127

References

Kumar S, Kumar S, Kumar S, Gautam S. Spontaneous gallbladder perforation in a patient of situs inversus totalis, misdiagnosed as perforation peritonitis due to gas under the right dome of the diaphragm. BMJ Case Rep. 2015 Jun 29;2015:bcr2014208003. doi: 10.1136/bcr-2014-208003. PMID: 26123454; PMCID: PMC4488708.

Churpii IK, Churpii KL, Churpii VK. Changes in parameters of the cardio-vascular system in patients with peritonitis, depending on its prevalence on admission. Reports of Vinnytsia National Medical University. 2014;(1 Suppl 1): 140-2. Ukrainian.

Kondratenko PH, editor. Khirurhiia: textbook. Kyiv: Medicine; 2009. 968 p. Ukrainian. ISBN 978-966-10-0036-9.

Alekseev SA. Abdominalny surgical sepsis. Minsk: Unipack; 2005. 252 p. Russian. ISBN 985-6745-49-7.

Hantimurov AV. Functional features of the kidney and liver vascular bed in acute diffuse peritonitis and its complications. Achievements of Clinical and Experimental Medicine. 2016 May 9;26(2):17-9. Ukrainian. doi:10.11603/1811-2471.2016.v26.i2.6235.

Oettgen P. Transcriptional regulation of vascular development. Circ Res. 2001 Aug 31;89(5):380-8. doi: 10.1161/hh1701.095958. PMID: 11532898.

Flynn A, Chokkalingam Mani B, Mather PJ. Sepsis-induced cardiomyopathy: a review of pathophysiologic mechanisms. Heart Fail Rev. 2010 Nov;15(6):605-11. doi: 10.1007/s10741-010-9176-4. PMID: 20571889.

Kosinets VA, Samsonova IV, Ryzhkovskaia EL. Structural changes in heart at experimental widespread purulent peritonitis. Khirurgiia (Mosk). 2012;(3):69-73. Russian. PMID: 22678541.

Huet O, Dupic L, Harrois A, Duranteau J. Oxidative stress and endothelial dysfunction during sepsis. Front Biosci (Landmark Ed). 2011 Jan 1;16:1986-95. doi: 10.2741/3835. PMID: 21196278.

Kursov SV. Hemodynamic variants of the course of shock in severe abdominal sepsis. Emergency medicine. 2011;(6):70-2. Russian.

Churpii IK.M indices of myocardial tissue at local and diffuse peritonitis. Hospital Surgery. Journal named by L.Ya. Kovalchuk. 2012;(1):62-4. Ukrainian.

Published
2020-12-28
How to Cite
Bilyayeva, O. O., & Karol, I. V. (2020). Investigation of the functional state changes of cardio-vascular system in patients, suffering peritonitis. Klinicheskaia Khirurgiia, 87(11-12), 23-27. https://doi.org/10.26779/2522-1396.2020.11-12.23
Section
General Problems of Surgery