Quality of life of treated patients with Mirizi syndrome

Keywords: Mirizzi syndrome; quality of life, cholelithiasis.

Abstract

Objective. To compare the quality of life of patients with spontaneous internal biliary fistula (SIBF) and without them, before and after surgery.

Materials and methods. 82 (38.7%) patients were diagnosed with Mirizzi syndrome (MS) type I, and 130 (61.3%) patients with type II (II-V) type MS. During the study, the classification of A. Csendes - M. Beltran was used. By sex, patients were distributed as follows: there were 68 men (32.0%), women - 144 (68.0%). The age of patients ranged from 37 to 80 years (average - 66.4 years). The GSRS (Gastrointestinal Symptom Rating Scale) questionnaire was used to assess quality of life. When comparing groups, the use of Student's T test comparative mean values and quadratic deviations. The reliability of the obtained p values were checked by the method of Bonferoni and False Discovery Rate (FDR).

Results. Multiple comparisons with Bonferon and FDR correction revealed statistically significant differences in the results between QOL of patients with MS I and II both before and after surgery. When compared on the scale of total measurement, it was found that the quality of life of patients without SIBF improved by 11% after cholecystectomy in MS I type. When comparing the results of QOL assessment before and after surgery in patients with type II MS, it was found that QOL after surgery in patients improved by 10% from baseline.

Conclusions. The quality of life of patients with MS I type is higher compared to patients with SIBF both before and after surgery (p=0.0001), which is due to impaired bile duct and gastrointestinal tract in SIBF. Elimination of SIBF improves the level of QOL of patients by 10%, which is characterized by a decrease in all items of the GSRS scale.

Author Biography

F. M. Pavuk, Uzhhorod National University

Pavuk Fedir M. MD, Postgraduate student,
assistant of the surgery department
Uzhhorod National Universitet
22 Victory str, Uzhhorod, 88018, Ukraine,
+380683783249
fedjapavuk111@gmail.com
https://orcid.org/0000-0001-6721-9806

References

Syplyviy V, Ievtushenko D, Petrenko G, Ievtushenko A. Surgical management of patients with Mirizzi syndrome. HPB. 2016;18(Suppl 2):e674-e5. doi: 10.1016/j.hpb.2016.01.033.

Dutka Y, Chooklin S. The special features of surgical treatment of patients with the Mirizzi syndrome. HPB. 2016;18:e820. doi: https://doi.org/10.1016/j.hpb.2016.01.389.

Zaporozhchenko B, Bondarets D, Borodaev I, Kachanov V, Muravyov P, Zubkov O, et al. Modern diagnostic methods and approaches to the surgical treatment of Mirizzi syndrome. Ukrainian Journal of Surgery. 2018;(4):33-7. Rbssian. doi: 10.22141/1997-2938.4.35.2017.118890.

Booij KAC, de Reuver PR, van Dieren S, van Delden OM, Rauws EA, Busch OR, et al. Long-term Impact of Bile Duct Injury on Morbidity, Mortality, Quality of Life, and Work Related Limitations. Ann Surg. 2018 Jul;268(1):143-50. doi: 10.1097/SLA.0000000000002258. PMID: 28426479.

Flores-Rangel GA, Chapa-Azuela O, Rosales AJ, Roca-Vasquez C, Böhm-González ST. Quality of Life in Patients with Background of Iatrogenic Bile Duct Injury. World J Surg. 2018 Sep;42(9):2987-91. doi: 10.1007/s00268-018-4564-3. PMID: 29520485.

Turan N, Aşt TA, Kaya N. Reliability and Validity of the Turkish Version of the Gastrointestinal Symptom Rating Scale. Gastroenterol Nurs. 2017 Jan/Feb;40(1):47-55. doi: 10.1097/SGA.0000000000000177. PMID: 28134719.

Deykalo ІM, Osadchuk DV, Karel OІ, Maknitskyi AV, Nazarko LR. Bouveret’s syndrome. Klin Khir. 2017 Dec 20;(12):78-9. Ukrainian.

Qurbonov N, Salim SD, Rakhmanov KE, Zayniyev AF. Current Trends in the Management of Mirizzi Syndrome: A Review of Literature. Annals of the Romanian Society for Cell Biology. 2021 Apr 10;25(4):1927-32.

Chon HK, Park C, Kim TH. Minimally Invasive Approach Using Digital Single-Operator Peroral Cholangioscopy-Guided Electrohydraulic Lithotripsy and Endoscopic Nasogallbladder Drainage for the Management of HighGrade Mirizzi Syndrome. Clin Endosc. 2021 Feb 18. doi: 10.5946/ce.2021.015. Epub ahead of print. PMID: 33596635.

Tyvonchuk OS, Tereshkevich IS, Babii IV. Laparoscopic removal of concrement in Bouveret syndrome. Klin khir. 2020 Jun 26;87(3-4):102-4. Ukrainian. doi: 10.26779/2522-1396.2020.3-4.102

Sato H, Hiraki M, Miyoshi A, Ikeda S, Koga H, Kitahara K. The strategy for Mirizzi syndrome type II with laparoscopic surgery: A case report. Int J Surg Case Rep. 2020;77:673-676. doi: 10.1016/j.ijscr.2020.11.106. Epub 2020 Nov 21. PMID: 33395871; PMCID: PMC7710499.

Roschyn GG, Tutchenko MI, Iskra NI, Rudyk DV. Some diagnostic and therapeutic aspects of Bouveret syndrome. Health of Society. 2017;(3):47-50 doi: 10.22141/2306-2436.6.3.2017.123491.

Published
2021-03-28
How to Cite
Pavuk, F. M. (2021). Quality of life of treated patients with Mirizi syndrome. Klinicheskaia Khirurgiia, 88(1-2), 69-72. https://doi.org/10.26779/2522-1396.2021.1-2.69
Section
General Problems of Surgery