Possibilities of the indocyanine green dye application for evaluation of peculiarities of lymph outflow and metastasizing of colorectal cancer

Keywords: colorectal cancer; indocyanine green; NTIT–operations.

Abstract

Objective. Studying of velocity of prevalence of luminescent dye indocyanine green along lymphatic vessels in the large bowel surgery.

Materials and methods. Estimation of procedure for coloring of tumoral substrate and lymphatic vessels while performance of oncological operations was conducted. We performed laparoscopic resection of sigmoid colon in 7 patients, suffering tumors, and anterior rectal resection in 5 patients, having tumors of upper ampullary part of rectum, using indocyanine green dye.

Results. In Group I, consisting of 7 patients, surgical technique of no touch manipulations on the tumor before transection of feeding vessels (NTIT–operations) was applied, and in Group II, consisting of 5 patients, the tumor mobilization was done primarily. Application of indocyanine green dye helped a lot to establish localization and prevalence of the process in rectum.

Conclusion. Application of fluorescent dye indocyanine green on tumoral substrate before doing ligation of feeding vessels raises possibility of the complication occurrence, consisting of the cancer cells dissemination in abdominal cavity. While performing laparoscopic procedures in resection of the large bowel tumors it is expedient to ligate the feeding vessels primarily, with secondary manipulation– to dissect and mobilize the tumoral substrate.

Author Biographies

V. V. Grubnik, Odessa National Medical University

Grubnіk Volodymyr Volodymyrovich, MD, DSci, Professor
Head of the Department of Surgery No. 1
Odessa National Medical University,
26/32 Zabolotny str, Odessa, 65025, Ukraine
0487500116,
algrub@i.ua,
https://orcid.org/0000-0003-4389-908X

R. P. Nikitenko, Odessa National Medical University

Nikitenko Raisa Petrivna, MD, PhD, Associate Professor of the Department of Surgery No. 1
Odessa National Medical University,
26/32 Zabolotny str, Odessa, 65025, Ukraine
+380962363303,
nikitenkoraja@rambler.ru
https://orcid.org/0000-0003-4214-5534

V. V. Mishchenko, Odessa National Medical University

Mishchenko Vasiliy Vasilevich MD, DSci, Professore
Department of Surgery No. 1
Odessa National Medical University,
26/32 Zabolotny str, Odessa, 65025, Ukraine
+380487500116,
https://orcid.org/0002–5951–3463

V. V. Ilyashenko, Odessa National Medical University

Ilyashenko V.V., MD, PhD, Associate Professor
Department of Surgery No. 1
Odessa National Medical University,
26/32 Zabolotny str, Odessa, 65025, Ukraine
+380487500116,
https://orcid.org/0000-0002-4636-5799

S. P. Degtyarenko, Odessa National Medical University

Degtyarenko S.P., MD, PhD, Associate Professor
Department of Surgery No. 1
Odessa National Medical University,
26/32 Zabolotny str, Odessa, 65025, Ukraine
+380487500116
https://orcid.org/0000–0002–1620–1718.

R. S. Parfentiev, Odessa National Medical University

Parfentiev Roman Sergeevich, MD, PhD, Associate Professor
Department of Surgery No. 1
Odessa National Medical University,
26/32 Zabolotny str, Odessa, 65025, Ukraine
0487500116,
rommul23@gmail.com,
https://orcid.org/0000-0002-4058-7534

A. N. Kvasha, Odessa National Medical University

Kvasha Oleksandr Mikolayovich, MD PhD, Associate Professor
Department of Surgery No. 1
Odessa National Medical University,
26/32 Zabolotny str, Odessa, 65025, Ukraine
+380674868495,
kanuro514@gmail.com
https://orcid.org/ 0000–0002–4019–9494

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Published
2021-07-28
How to Cite
Grubnik, V. V., Nikitenko, R. P., Mishchenko, V. V., Ilyashenko, V. V., Degtyarenko, S. P., Parfentiev, R. S., & Kvasha, A. N. (2021). Possibilities of the indocyanine green dye application for evaluation of peculiarities of lymph outflow and metastasizing of colorectal cancer. Klinicheskaia Khirurgiia, 88(3-4), 64-68. https://doi.org/10.26779/2522-1396.2021.3-4.64
Section
General Problems of Surgery

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