Changes of hematological indices in patients with diffuse toxic goiter

Keywords: diffuse toxic goiter; anemia, degree of the anemia severity, morphological types of anemia.

Abstract

Objective. To reveal the incidence of various morphological types and degrees of the anemia severity in patients with diffuse toxic goiter.

Materials and methods. Data of medical histories of 157 patients, operated for diffuse toxic goiter in 2012 yr were analyzed. In accordance to hematological indices estimated there were outlined two Groups of patients: Group I – 98 patients with diffuse toxic goiter and mild anemia, average age (39.4 ± 1.4) yrs old, 57 (58.2%) women and 41 (41.8%) men, and Group II – 59 patients with diffuse toxic goiter and middle degree of the anemia severity, average age (41.1 ± 1.7) yrs old, 48 (81.4%) women and 11 (18.6%) men. Levels of hemoglobin, hematocrit, quantity and average volume of erythrocytes, average content of hemoglobin in one erythrocyte, average concentration of hemoglobin in the erythrocytes were determined in the blood analysis.

Results. Microcytic type of anemia was noted in 89.8% of patients with anemia of middle degree of severity, while a normocytic one – in 10.2%; in mild anemia – in 87.8 and 12.2% patients, accordingly. Hypochromic and normochromic types of anemia with equal rate were revealed in mild anemia and anemia of middle degree of severity: hypochromic – in 94.9%, normochromic – in 5.1% patients.

Conclusion. Diffuse toxic goiter is characterized by more frequent development of mild (62.4%), microcytic (88.5%), hyperchromic (94.9%) anemia, caused by iron deficiency.

Author Biographies

F. H. Saidova, Scientific Centre of Surgery named after acad. M. A. Topchibashev, Baku, Republic of Azerbaijan

Saidova Farida Kheyraddin MD, DSci(Med), professor,
Chief of department of endocrine surgery
Scientific Center of Surgery named after M.A.Topchubashov,
Azerbaycan, Baku,Yasamal district, st. Sharifzade 196
farida.s.x@mail.ru
https://orcid.org/0000–0002–9511–7927

L. M. Ahmedova, Azerbaijan State Advanced Training Institute of Doctors named after A. Aliyev, Baku

Ahmedova Leyli Mamed MD, PhD, Senior Scientist
Central Scientific Research Laboratory,
Azerbaijan State Advanced Traininq Institute for Doctors named after A.Aliyev,
Azerbaycan, Baku, Yasamal district, Tbilisi Avenue 3165
leyli.48@mail.ru
https://orcid.org/0000–0002–6941–6042

Zh. B. Aslanova, Scientific Centre of Surgery named after acad. M. A. Topchibashev, Baku, Republic of Azerbaijan

Aslanova Jale Baba Junior Researcher
Department of endocrine surgery
Scientific Center of Surgery named after M.A.Topchubashov,
Azerbaycan, Baku, Yasamal district, st. Sharifzade 196,
jal–aslanova2005@yandex.com
https://orcid.org/0000–0002–3981–4883

N. A. Najafov, Scientific Centre of Surgery named after acad. M. A. Topchibashev, Baku, Republic of Azerbaijan

Najafov Namik Alysh MD, PhD
chief of the Department of Clinical Laboratory Diagnostics of the Scientific
Center of Surgery named after M.A.Topchibashov,
Azerbaycan, Baku, Yasamal district, st. Sharifzade 196
n_namiq@rambler.ru
https://orcid.org/0000–0003–3177 –5995

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Published
2021-07-28
How to Cite
Saidova, F. H., Ahmedova, L. M., Aslanova, Z. B., & Najafov, N. A. (2021). Changes of hematological indices in patients with diffuse toxic goiter. Klinicheskaia Khirurgiia, 88(3-4), 76-79. https://doi.org/10.26779/2522-1396.2021.3-4.76
Section
General Problems of Surgery