Impact of biliopancreatic shunting in modification of Hess–Marceau on indices of lipidogram in patients, suffering morbid obesity and dyslipidemia

Keywords: morbid obesity; dyslipidemia; biliopancreatic shunting; results

Abstract

Objective. To study the impact of biliopancreatic shunting (BPSH) in modification of Hess–Marceau on indices of lipidogram in patients, suffering morbid obesity and dyslipidemia.

Маterials and methods. The investigation was based on data of clinical examination and results of surgical treatment in 100 patients, suffering morbid obesity, to whom BPSH in modification of Hess–Marceau was conducted. There were 60 women and 40 men. Middle age of the patients have constituted (45 ± 8.2) yrs old.

Resullts. Laboratory markers of predominantly atherogenic phenotypes of dyslipidemia were registered preoperatively in 75 (75%) patients. Median level of general cholesterol have lowered down from (6.14 ± 0.9) tо (3.7 ± 0.7) mmol/l, triglycerides – from (1.98 ± 0.9) tо (1.12 ± 0.4) mmol/l, regression of the atherogenecity coefficient – from (3.9 ± 0.9) tо (23 ± 1.1) in 60 mo after bariatric surgery (р < 0.05). The indices of lipidogram have normalized in 87.0%, and improved – in 13.0% of the patients.

Conclusion. BPSH in modification of Hess–Marceau constitutes a highly effective procedure for correction of dyslipidemia in patients, suffering morbid obesity.

Author Biographies

I. M. Todurov, Centre of Innovative Medical Technologies NAS of Ukraine, Kyiv

Todurov I. M.: MD, DSci, professor,
director of Center for Innovative Medical Technologies
Kyiv, 04053 Voznesensʹkyy uzviz 22 st
+38 044 272 12 38
todurov@nas.gov.ua
https://orcid.org/0000-0001-6170-6056

O. V. Perekhrestenko, Centre of Innovative Medical Technologies NAS of Ukraine, Kyiv

Perekhrestenko O. V.: MD, PhD,
vice-director of Center for Innovative Medical Technologies,
Kyiv, 04053 Voznesenskyy uzviz 22 st
+38 044 272-50-06
perekhrestenko@nas.gov.ua
https://orcid.org/0000-0002-8240-7095.

S. V. Kosiuchno, Centre of Innovative Medical Technologies NAS of Ukraine, Kyiv

Kosiuchno S. V.: MD, PhD,
scientific chief department of minimally invasive surgery
Center for Innovative Medical Technologies,
Kyiv, 04053 Voznesenskyy uzviz 22 st
+38 044 272 2266
kosiukhno@nas.gov.ua
https://orcid.org/0000-0002-2950-9279

O. O. Kalashnikov, Centre of Innovative Medical Technologies NAS of Ukraine, Kyiv

Kalashnikov O. O.: MD, PhD,
head of surgical department,
Center for Innovative Medical Technologies,
Kyiv, 04053 Voznesenskyy uzviz 22 st
+38 044 272 2266
4542086@gmail.com
https://orcid.org/0000-0002-8224-8039

O. I. Plehutsa, Centre of Innovative Medical Technologies NAS of Ukraine, Kyiv

Plehutsa O. I.: MD, PhD,
senior researcher department of endocrine and metabolic surgery
Center for Innovative Medical Technologies,
Kyiv, 04053 Voznesensʹkyy uzviz 22 st
+38 044 272 21 86
plehutsamd@gmail.com
https://orcid.org/0000-0002-5695-6111

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Published
2019-02-28
Section
General Problems of Surgery